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Damnacanthal

Cat. No. :YN250165

  • CAS No. :477-84-9

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    • Product Name:Damnacanthal
      CAS NO.:477-84-9
      Chemical Name:
      Synonyms:
      Molecular Weight:282.25
      Molecular Formula:C₁₆H₁₀O₅
      SMILES:O=CC(C(OC)=C1C2=O)=C(O)C=C1C(C3=C2C=CC=C3)=O
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:Damnacanthal is an anthraquinone isolated from the root ofMorinda citrifolia. Damnacanthal is a highly potent, selective inhibitor ofp56lcktyrosine kinaseactivity. Natural Damnacanthal inhibitsp56lckautophosphorylation and phosphorylation of exogenous substrates with IC50s of 46nM and 220nM, respectively. Damnacanthal is a potent inducer ofapoptosiswith anticancer activity. Damnacanthal also has antinociceptive, anti-inflammatory effects in mice and anti-fungal activity againstC and ida albicans.
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