Damnacanthal
Cat. No. :YN250165
CAS No. :477-84-9
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Product Name: | Damnacanthal |
CAS NO.: | 477-84-9 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 282.25 |
Molecular Formula: | C₁₆H₁₀O₅ |
SMILES: | O=CC(C(OC)=C1C2=O)=C(O)C=C1C(C3=C2C=CC=C3)=O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Damnacanthal is an anthraquinone isolated from the root ofMorinda citrifolia. Damnacanthal is a highly potent, selective inhibitor ofp56lcktyrosine kinaseactivity. Natural Damnacanthal inhibitsp56lckautophosphorylation and phosphorylation of exogenous substrates with IC50s of 46nM and 220nM, respectively. Damnacanthal is a potent inducer ofapoptosiswith anticancer activity. Damnacanthal also has antinociceptive, anti-inflammatory effects in mice and anti-fungal activity againstC and ida albicans. |
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