Isoliquiritin
Cat. No. :YN251528
CAS No. :5041-81-6
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order@ubiochem.com| Product Name: | Isoliquiritin |
| CAS NO.: | 5041-81-6 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 418.39 |
| Molecular Formula: | C₂₁H₂₂O₉ |
| SMILES: | O[C@H]([C@@H](O)[C@@H]1O)[C@@H](O[C@@H]1CO)OC2=CC=C(/C=C/C(C(C=CC(O)=C3)=C3O)=O)C=C2 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Insampaedoksan is a traditional herbal medicine used for antipyretic and antiinflammatory diseases, isoliquiritigenin is the main compound of it , thus , isoliquiritigenin has bioactivity effects such as antioxidant, estrogenic and anticancer. Isoliquiritin, liquiritin,and isoliquirigenin induce apoptotic cell death through upregulating p53 and p21 in the A549 non-small cell lung cancer cells and inhibit the p53-dependent pathway and showed crosstalk between Akt activities,suggests they can be an alternative agent for the treatment of lung cancer. Isoliquiritin and liquiritin produce significant antidepressant-like effects, and their mechanism of action may be due to increased 5-HT and NE in the mouse hippocampus, hypothalamus and cortex. Isoliquiritin has antifungal activity, and has inhibitory effect against peronophythora litchi chen through a membrane damage mechanism. |
| IC50&Target: | |
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| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
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