YN250702 Posaconazole 171228-49-2

Posaconazole is an inhibitor primarily of CYP3A4, but it does not inhibit the activity of other CYP enzymes Also an inhibitor of sterol C14ɑ demethylase inhibitor with IC50 of 0.25 μM. Posaconazole has a median terminal elim...

YN250187 Tavaborole 174671-46-6

Tavaborole (AN-2690) is a boron-containing small molecule with broad spectrum antifungal activity.

YN250028 AN2718 174672-06-1

AN2718 inhibits fungal growth by blocking protein synthesis using the oxaborole tRNA trapping (OBORT) mechanism.

YN250584 Ravuconazole 182760-06-1

Ravuconazole (BMS-207147;ER-30346) is an orally available triazoleantifungle agent that potently inhibits a wide range of fungi.

YN250586 Luliconazole 187164-19-8

Luliconazole is a broad-spectrum antifungal drug.

YN250040 Fosfluconazole 194798-83-9

Fosfluconazole is a water-soluble phosphate prodrug of fluconazole, which is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections.

YN250741 Flumorph 211867-47-9

Flumorph(SYP-L190) is a carboxylic acid amide (CAA) fungicide.

YN251859 Bac2A TFA 231306-42-6

Bac2A TFA is anantimicrobial and immunomodulatory peptide. Bac2A TFA is a linear variant of bactenecin and is very effective against fungal pathogens.

YN250756 Micafungin 235114-32-6

Micafungin (Mycamine; FK463) is an echinoc and in antifungal drug which can inhibit 1,3-beta-D-glucan synthase.

YN250739 (S,S)-Valifenalate 283159-94-4

(S,S)-Valifenalate ((S,S)-IR5885) is an acylamino acidfungicide and is used to control a wide range of fungi belonging to the class of Oomycetes. (S,S)-Valifenalate ((S,S)-IR5885) interferes with the cell-wall synthesis thus...

YN250035 Ferrostatin-1 347174-05-4

Ferrostatin-1 (Fer-1) is a potent and selective inhibitor of ferroptosis with EC50 of 60 nM.

YN250351 Filastatin 431996-53-1

Filastatin is a long-lasting inhibitor ofC and ida albicansfilamentation. Filastatin inhibits adhesion by multiple pathogenicC and idaspecies with an IC50 of ~3μM in the GFP-based adhesion assay. Filastatin inhibitsfungaladhesio...

YN250383 Sordarin sodium 463356-00-5

Sordarin is a potent diphthamide-dependenteEF2inhibitor withantifungalproperties. Sordarin targets eEF2 so as to inhibit protein translation by blocking eEF2-mediated translocation of tRNAs. Sordarin inhibits translation specifi...

YN250359 iKIX1 656222-54-7

iKIX1 is anantifungal agent and resensitizes drug-resistantC. glabratato azole antifungals in vitro. iKIX1 inhibits the interaction between the KIX domain of the mediator subunitCgGal11A and the activation domain ofCgPdr1, ...

YN250277 Fluopyram 658066-35-4

Fluopyram is asuccinate dehydrogenaseinhibitor fungicide, inhibits the growth ofF. virguliformeisolates with mean EC50of 3.35 µg/mL.

YN250527 Triclopyricarb 902760-40-1

Triclopyricarb (SYP-7017) is a strobilurin fungicide that can be used in crops disease control. Triclopyricarb inhibits mycelial growth withEC50values ranged from 0.006 µg/mL to 0.047 µg/mL.

YN250781 E1210 936339-60-5

E1210 is a first-in-class, broad-spectrum and orally active antifungal. E1210 has a mechanism of action-inhibition of fungal glycosylphosphatidylinositol (GPI) biosynthesis.

YN250022 Isavuconazonium sulfate 946075-13-4

Isavuconazonium sulfate (BAL8557-002), the prodrug of the active triazole Isavuconazole, is an orally active antifungal agent. Isavuconazonium sulfate is used for invasive aspergillosis and mucormycosis.

YN250424 Isoeleutherin 1078723-14-4

Isoeleutherin is a naphthopyran derivative isolated fromE. americana Merr. Et Heynewith anti-fungal, anti-viral, and anti-tumor activities. Isoeleutherin plays an important role in selective modulation of T helper cell-mediated imm...

YN250704 Posaconazole-D4 1133712-26-1

Posaconazole-D4 is a deuterium-labeled form of Posaconazole. Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity.