Dolutegravir
Cat. No. :YN371361
CAS No. :1051375-16-6
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order@ubiochem.com| Product Name: | Dolutegravir |
| CAS NO.: | 1051375-16-6 |
| Chemical Name: | |
| Synonyms: | S/GSK1349572 |
| Molecular Weight: | 419.38 |
| Molecular Formula: | C₂₀H₁₉F₂N₃O₅ |
| SMILES: | FC1=CC(F)=C(C=C1)CNC(C2=CN(C3=C(C2=O)O)C[C@@]([H])(N4C3=O)OCC[C@H]4C)=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Dolutegravir (GSK1349572) is a two-metal-binding HIV integrase inhibitor with IC50 of 2.7 nM in a cell-free assay, modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H. |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
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