Raltegravir
Cat. No. :YN370279
CAS No. :518048-05-0
86-020-82000279
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order@ubiochem.com| Product Name: | Raltegravir |
| CAS NO.: | 518048-05-0 |
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| Molecular Weight: | 444.42 |
| Molecular Formula: | C₂₀H₂₁FN₆O₅ |
| SMILES: | O=C(C(O)=C(C(NCC1=CC=C(C=C1)F)=O)N=C2C(C)(C)NC(C3=NN=C(C)O3)=O)N2C |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Raltegravir (MK-0518) is a potent integrase (IN) inhibitor for WT and S217Q PFV IN with IC50 of 90 nM and 40 nM in cell-free assays, respectively. It shows greater than 1000-fold selectivity for HIV-1 IN over several related Mg2+-dependent enzyme such as HCV polymerase, HIV reverse transcriptase, HIV RNaseH and human α-, β-, γ-polymerases. |
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