Doravirine
Cat. No. :YN250682
CAS No. :1338225-97-0
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Product Name: | Doravirine |
CAS NO.: | 1338225-97-0 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 425.75 |
Molecular Formula: | C₁₇H₁₁ClF₃N₅O₃ |
SMILES: | N#CC1=CC(OC2=C(C(F)(F)F)C=CN(CC(N3C)=NNC3=O)C2=O)=CC(Cl)=C1 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Doravirine is a novel HIV-1 nonnucleoside reverse transcriptase inhibitor with IC50 values of 12, 9.7, and 9.7 nM against the wild type (WT) and K103N and Y181C reverse transcriptase (RT) mutants, respectively, in a biochemical assay. It is highly specific with minimum off-target activities. |
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