Myriocin
Cat. No. :YN251717
CAS No. :35891-70-4
Product Name: | Myriocin |
CAS NO.: | 35891-70-4 |
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Molecular Weight: | 401.54 |
Molecular Formula: | C₂₁H₃₉NO₆ |
SMILES: | CCCCCCC(CCCCCC/C=C/C[C@@H](O)[C@H](O)[C@](CO)(N)C(O)=O)=O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Myriocin, a fungal metabolite isolated fromMyriococcum albomyces,Isaria sinclairi and Mycelia sterilia, is a potent inhibitor ofserine-palmitoyl-transferase (SPT) and a key enzyme in de novo synthesis of sphingolipids. Myriocin strongly suppresses replication of both the subgenomic HCV-1b replicon and the JFH-1 strain of genotype 2a infectious HCV , with an IC50 of 3.5 µg/mL for inhibiting HCV infection. |
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