CU-T12-9
Cat. No. :YN330101
CAS No. :1821387-73-8
86-020-82000279
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order@ubiochem.com| Product Name: | CU-T12-9 |
| CAS NO.: | 1821387-73-8 |
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| Molecular Weight: | 362.31 |
| Molecular Formula: | C₁₇H₁₃F₃N₄O₂ |
| SMILES: | CNC1=CC=C(C=C1N2C=C(N=C2)C3=CC=C(C=C3)C(F)(F)F)[N+]([O-])=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | CU-T12-9 is a specificTLR1/2agonist withEC50of 52.9nM in HEK-Blue hTLR2 SEAP assay. CU-T12-9 activates both the innate and the adaptive immune systems. CU-T12-9 selectively activates the TLR1/2 heterodimer, not TLR2/6. CU-T12-9 signals through NF-κB and invokes an elevation of the downstream effectors TNF-α, IL-10, and iNOS. |
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