N-Desmethylclozapine
Cat. No. :YN321700
CAS No. :6104-71-8
86-020-82000279
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order@ubiochem.com| Product Name: | N-Desmethylclozapine |
| CAS NO.: | 6104-71-8 |
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| Molecular Weight: | 312.80 |
| Molecular Formula: | C₁₇H₁₇ClN₄ |
| SMILES: | ClC1=CC=C2C(N=C(N3CCNCC3)C4=CC=CC=C4N2)=C1 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | N-Desmethylclozapine is a major active metabolite of the atypical antipsychotic drug Clozapine. N-Desmethylclozapine is a potent, allosteric and partialM1 receptorsagonist (EC50=115nM) and is able to potentiate hippocampal N-methyl-d-aspartate (NMDA) receptor currents through M1 receptor activation. N-Desmethylclozapine is also aδ-opioidagonist. |
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