Tenofovir alafenamide hemifumarate
Cat. No. :YN250623
CAS No. :1392275-56-7
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Product Name: | Tenofovir alafenamide hemifumarate |
CAS NO.: | 1392275-56-7 |
Chemical Name: | |
Synonyms: | TAF hemifumarate, GS-7340 hemifumarate |
Molecular Weight: | 534.50 |
Molecular Formula: | C₂₁H₂₉N₆O₅P.₁/₂ C₄H₄O₄ |
SMILES: | O=C(O)/C=C/C(O)=O.NC1=NC=NC2=C1N=CN2C[C@@H](C)OC[P@](OC3=CC=CC=C3)(N[C@@H](C)C(OC(C)C)=O)=O.[0.5] |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Tenofovir alafenamide (TAF, GS-7340) hemifumarate is a prodrug of tenofovir but results in significantly higher intracellular tenofovir concentrations and lower serum levels. Tenofovir alafenamide is a novel nucleotide reverse transcriptase inhibitor for the treatment of HIV-1 infection. |
IC50&Target: | |
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Clinical Trial: | |
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References: |
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