UKI-1
Cat. No. :YN480059
CAS No. :220355-63-5
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5mg
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Product Name: | UKI-1 |
CAS NO.: | 220355-63-5 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 613.81 |
Molecular Formula: | C₃₂H₄₇N₅O₅S |
SMILES: | O=C(N1CCN(C([C@@H](NS(=O)(C2=C(C(C)C)C=C(C(C)C)C=C2C(C)C)=O)CC3=CC=CC(C(N)=N)=C3)=O)CC1)OCC |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | UKI-1 is a novel synthetic inhibitor of the urokinase-type plasminogen activator system. It can also inhibits the invasive capacity of carcinoma cells. (Ki=0.41μM) In vitro : A decrease of tumor cell invasion by up to 50% was achieved in both models with the SCCHN line FaDu and the cervical carcinoma line HeLa after treatment with UK1. |
IC50&Target: | |
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Clinical Trial: | |
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References: |
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