TH1020
Cat. No. :YN330152
CAS No. :1841460-82-9
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5mg
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10mg
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Product Name: | TH1020 |
CAS NO.: | 1841460-82-9 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 453.54 |
Molecular Formula: | C₂₃H₁₅N₇S₂ |
SMILES: | C12=NC=NC(SC3=NN=C(N3CC4=CC=CC=C4)C5=CC=NC=C5)=C1SC6=NC=CC=C62 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | TH1020 is a potent and selectivetoll-like receptor 5 (TLR5)/flagellin complexantagonist with an IC50 of 0.85μM. TH1020 inhbits flagellin-inducedTLR5signaling. TH1020 is inactive against TLR2, TLR3, TLR4, TLR7 and TLR8. |
IC50&Target: | |
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Clinical Trial: | |
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References: |
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