Mitoguazone
Cat. No. :YN250135
CAS No. :459-86-9
Product Name: | Mitoguazone |
CAS NO.: | 459-86-9 |
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Molecular Weight: | 184.20 |
Molecular Formula: | C₅H₁₂N₈ |
SMILES: | CC(/C=N/NC(N)=N)=NNC(N)=N |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Mitoguazone (Methylglyoxal-bis(guanylhydrazone)) is a synthetic polycarbonyl derivative with potent antineoplastic activity. Mitoguazone is a brain-penetrant and competitiveS-adenosyl-methionine decarboxylase (SAMDC)inhibitor that disruptspolyamine biosynthesis. Mitoguazone induces cellapoptosis. Mitoguazone inhibitsHIVDNA integration into the cellular DNA in both monocytes and macrophages. Mitoguazone has the potential for acute leukemia, Hodgkin's and non-Hodgkin's lymphoma treatment. |
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