HQNO
Cat. No. :YN371224
CAS No. :341-88-8
86-020-82000279
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order@ubiochem.com| Product Name: | HQNO |
| CAS NO.: | 341-88-8 |
| Chemical Name: | |
| Synonyms: | 2-heptyl-4-hydroxyquinoline-N-oxide |
| Molecular Weight: | 259.34 |
| Molecular Formula: | C₁₆H₂₁NO₂ |
| SMILES: | OC(C1=C2C=CC=C1)=CC(CCCCCCC)=N2=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | HQNO is a natural quinolone secreted by P. aeruginosa. HQNO is a potent inhibitor of the electron transport chain with Kd of 64 nM for the ubiquinol-ferricytochrome c oxidoreductase segment (Complex III) of the respiratory chain. HQNO is also an inhibitor of bacterial and mitochondrialType II NADH : quinone oxidoreductase (NDH-2) with IC50 of 7.3 μM in the presence of 50μM menadione. |
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