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Filibuvir

Cat. No. :YN250050

  • CAS No. :877130-28-4

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    • 5mg

      $ 360.00

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    • Product Name:Filibuvir
      CAS NO.:877130-28-4
      Chemical Name:
      Synonyms:
      Molecular Weight:503.64
      Molecular Formula:C₂₉H₃₇N₅O₃
      SMILES:O=C(O1)C(CC2=NN(C(C)=C3)C(N=C3C)=N2)=C(O)C[C@@]1(C4CCCC4)CCC5=CC(CC)=NC(CC)=C5
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:Filibuvir is a potent, selective non-nucleoside inhibitor (NNI) of theHCV nonstructural 5B protein (NS5B) RNA-dependent RNA polymerase, and it binds noncovalently in the “Thumb 2” pocket of NS5B. In vitro, filibuvir is equipotent against genotype 1a and 1b replicons, with an EC50 of 59nM.
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