Filibuvir
Cat. No. :YN250050
CAS No. :877130-28-4
Pack size
price
inventory
5mg
$ 360.00
Product Name: | Filibuvir |
CAS NO.: | 877130-28-4 |
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Molecular Weight: | 503.64 |
Molecular Formula: | C₂₉H₃₇N₅O₃ |
SMILES: | O=C(O1)C(CC2=NN(C(C)=C3)C(N=C3C)=N2)=C(O)C[C@@]1(C4CCCC4)CCC5=CC(CC)=NC(CC)=C5 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Filibuvir is a potent, selective non-nucleoside inhibitor (NNI) of theHCV nonstructural 5B protein (NS5B) RNA-dependent RNA polymerase, and it binds noncovalently in the “Thumb 2” pocket of NS5B. In vitro, filibuvir is equipotent against genotype 1a and 1b replicons, with an EC50 of 59nM. |
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