IMP-1088
Cat. No. :YN290125
CAS No. :2059148-82-0
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5mg
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10mg
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Product Name: | IMP-1088 |
CAS NO.: | 2059148-82-0 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 453.53 |
Molecular Formula: | C₂₅H₂₉F₂N₅O |
SMILES: | CN1N=C(CN(C)C)C2=C1C=CC(C3=CC=C(F)C(F)=C3OCCC4=C(C)N(C)N=C4C)=C2 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | IMP-1088 is a potenthuman N-myristoyltransferasesnMT1 and NMT2dual inhibitor with IC50s of <1nM for HsNMT1 and HsNMT2. IMP-1088 has aKdof <210 pM for HsNMT1. IMP-1088 efficiently blocksrhinovirus replicationby blocking rhinovirus virus-encoded protein (VP0) N-myristoylation. IMP-1088 protects host cells from the cytotoxic effects of viral infection. |
IC50&Target: | |
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Clinical Trial: | |
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References: |
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