G907
Cat. No. :YN250362
CAS No. :2244035-16-1
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order@ubiochem.com| Product Name: | G907 |
| CAS NO.: | 2244035-16-1 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 433.93 |
| Molecular Formula: | C₂₆H₂₄ClNO₃ |
| SMILES: | O=C(O)/C=C/C1=C(C2CC2)C3=CC(OC(C4=C(C5CC5)C=CC=C4Cl)C)=CC=C3N=C1 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | G907 is a selective small-molecule antagonist ofATP-binding cassette (ABC) transporter, MsbA. It inhibits purifiedE. coliMsbA in amphipols with an IC50 of 18nM. G907 traps MsbA in an inward-facing, lipopolysaccharide-bound conformation by wedging into an architecturally conserved transmembrane pocket. Bactericidal activity. |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
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