Hck-IN-1
Cat. No. :YN440216
CAS No. :1473404-51-1
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order@ubiochem.com| Product Name: | Hck-IN-1 |
| CAS NO.: | 1473404-51-1 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 402.81 |
| Molecular Formula: | C₁₆H₁₁ClN₆O₃S |
| SMILES: | S=C(N1N=C(C2=CC=C([N+]([O-])=O)C=C2)C(/N=N/C3=CC=CC(Cl)=C3)=C1O)N |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Hck-IN-1 (compound B9), a diphenylpyrazolo compound, is a selectiveNef-dependent Hckinhibitor with IC50s of 2.8μM, >20μM for Nef:Hck complex and Hck, respectively. Hck-IN-1 is a direct and wideHIV-1 Nefantagonists with an IC50 of 100-300nM for wild-type HIV-1 replication. Hck-IN-1 binds pocket residue Asn126 and has anti-retroviral activity. |
| IC50&Target: | |
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