bpV(phen)
Cat. No. :YN371683
CAS No. :42494-73-5
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order@ubiochem.com| Product Name: | bpV(phen) |
| CAS NO.: | 42494-73-5 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 350.24 |
| Molecular Formula: | C₁₂H₈KN₂O₅V |
| SMILES: | O=[V+3]12([N]3=CC=C4)([O-][O-]1)([O-][O-]2)[N]5=C6C3=C4C=CC6=CC=C5.[K+] |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | bpV(phen) is a potentprotein tyrosine phosphatase (PTP) and PTENinhibitor with IC50s of 38nM, 343nM and 920nM forPTEN,PTP-β and PTP-1B, respectively. bpV(phen) inhibits proliferation of the protozoanparasiteLeishmaniain vitro. bpV(phen) strongly induces the secretion of a large number of chemokines and pro-inflammatory cytokines, and it activates aTh1-typepathway (IL-12, IFNγ). bpV(phen) can also induce cellapoptosis, and has anti-angiogenic and anti-tumor activity . |
| IC50&Target: | |
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| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
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