NPD-1335
Cat. No. :YN371048
CAS No. :2376326-31-5
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order@ubiochem.com| Product Name: | NPD-1335 |
| CAS NO.: | 2376326-31-5 |
| Chemical Name: | |
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| Molecular Weight: | 455.55 |
| Molecular Formula: | C₂₈H₂₉N₃O₃ |
| SMILES: | O=C(NCC1=CC=CC=C1)C#CC2=CC(C3=NN(C(C)C)C([C@@]4([H])CC=CC[C@@]34[H])=O)=CC=C2OC |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | NPD1335 is aTrypanosoma brucei phosphodiesterase B1(TbrPDEB1) inhibitor with submicromolar activities againstT. bruceiparasites. NPD1335 displays a greatly improved cytotoxicity profile. NPD1335 increases intracellular cAMP levels and results in the distortion of the cell cycle and cell death. |
| IC50&Target: | |
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