PC945
Cat. No. :YN370862
CAS No. :1931946-73-4
86-020-82000279
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order@ubiochem.com| Product Name: | PC945 |
| CAS NO.: | 1931946-73-4 |
| Chemical Name: | |
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| Molecular Weight: | 682.73 |
| Molecular Formula: | C₃₈H₃₇F₃N₆O₃ |
| SMILES: | O=C(NC1=CC=C(F)C=C1)C(C=C2)=CC=C2N3CCN(C4=CC=C(OC[C@@H]5CO[C@](C6=CC=C(F)C=C6F)(CN7N=CN=C7)C5)C(C)=C4)CC3 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | PC945, a potent, long-actingantifungaltriazole, possesses activity against a broad range of both azole-susceptible and azole-resistant strains ofAspergillus fumigatus. PC945 is also a potent, tightly binding inhibitor ofA. fumigatussterol 14α-demethylase activity,CYP51A and CYP51B, with IC50s of 0.23μM and 0.22μM, respectively. |
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