TH1217
Cat. No. :YN250511
CAS No. :1862212-48-3
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order@ubiochem.com| Product Name: | TH1217 |
| CAS NO.: | 1862212-48-3 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 491.09 |
| Molecular Formula: | C₂₀H₁₇BCl₂N₄O₆ |
| SMILES: | CC1=NC2=C(C(Cl)=C(Cl)C=C2N1CC3=CC=C(C=C3)[B-]45OC(C[N+]4(C)CC(O5)=O)=O)[N+]([O-])=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | TH1217 (ZINC1775962367) is a potent and selectivedCTPase pyrophosphatase 1 (dCTPase)inhibitor, with an IC50 of 47nM. TH1217 enhances the cytotoxic effect of cytidine analogues in leukemia cells. TH1217 also could modulate SARS-Cov-2 interactors, so it shows activity of against COVID-19. |
| IC50&Target: | |
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| In Vivo: | |
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| Solvent & Solubility: | |
| References: |
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