K777
Cat. No. :YN320522
CAS No. :233277-99-1
Pack size
price
inventory
10mg
$ 880.00
86-020-82000279
sales@ubiochem.com
order@ubiochem.com| Product Name: | K777 |
| CAS NO.: | 233277-99-1 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 574.73 |
| Molecular Formula: | C₃₂H₃₈N₄O₄S |
| SMILES: | O=C(N1CCN(C)CC1)N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CCC3=CC=CC=C3)/C=C/S(=O)(C4=CC=CC=C4)=O)=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | K777 is a potent, orally active and irreversiblecysteine proteaseinhibitor. K777 is also a potentCYP3A4inhibitor with an IC50 of 60nM and a selectiveCCR4antagonist featuring the potent chemotaxis inhibition. K777 irreversibly inhibits Cruzain, the major cysteine protease ofTrypansoma cruzi, and cathepsins B and L. K777 is a broad-spectrum antiviral by targeting cathepsin-mediated cell entry. K777 inhibitsSARS-CoV and EBOVpseudovirus entry with IC50 values of 0.68nM and 0.87nM, respectively . |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
TELL : +86-020-82000279
Add:Room 519, Block F, Guangzhou International Business Incubator, No.3 Lanyue Road, Science Town, Huangpu District, Guangzhou, China.
