Destruxin B
Cat. No. :YN270566
CAS No. :2503-26-6
Pack size
price
inventory
5mg
$ 2,750.00
Product Name: | Destruxin B |
CAS NO.: | 2503-26-6 |
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Molecular Weight: | 621.81 |
Molecular Formula: | C₃₂H₅₅N₅O₇ |
SMILES: | O=C(N[C@]([C@@H](C)CC)(C)C(N(C)[C@@H](C(C)C)C(N(C)[C@@H](C)C(NCC1)=O)=O)=O)[C@@](CCC2)(C)N2C([C@@H](CC(C)C)OC1=O)=O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Destruxin B, isolated from entomopathogenic fungusMetarhizium anisopliae, is one of the cyclodepsipeptides with insecticidal and anticancer activities. Destruxin B induces apoptosis via aBcl-2 Family-dependent mitochondrial pathway in human nonsmall cell lung cancer cells. Destruxin B significantly activatescaspase-3 and reduces tumor cell proliferation through caspase-mediatedapoptosis, not only in vitro but also in vivo. |
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