NF279
Cat. No. :YN360901
CAS No. :202983-32-2
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Product Name: | NF279 |
CAS NO.: | 202983-32-2 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 1401.12 |
Molecular Formula: | C₄₉H₃₀N₆Na₆O₂₃S₆ |
SMILES: | O=C(NC1=CC=C(C=C1)C(NC2=CC=C(C=C2)C(NC3=CC=C(S(=O)(O[Na])=O)C4=CC(S(=O)(O[Na])=O)=CC(S(=O)(O[Na])=O)=C34)=O)=O)NC5=CC=C(C=C5)C(NC6=CC=C(C=C6)C(NC7=CC=C(S(=O)(O[Na])=O)C8=CC(S(=O)(O[Na])=O)=CC(S(=O)(O[Na])=O)=C78)=O)=O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | NF279 is a potent selective and reversibleP2X1 receptorantagonist, with an IC50 of 19nM. NF279 displays good selectivity over P2X2, P2X3 (IC50=1.62μM), P2X4 (IC50>300μM). NF279 is a dual HIV-1 coreceptor inhibitor that interferes with the functional engagement of CCR5 and CXCR4 by Env. |
IC50&Target: | |
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In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: | |
References: |
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