Fluconazole mesylate
Cat. No. :YN250908
CAS No. :159532-41-9
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order@ubiochem.com| Product Name: | Fluconazole mesylate |
| CAS NO.: | 159532-41-9 |
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| Molecular Weight: | 402.38 |
| Molecular Formula: | C₁₄H₁₆F₂N₆O₄S |
| SMILES: | FC1=CC=C(C(O)(CN2C=NC=N2)CN3C=NC=N3)C(F)=C1.CS(=O)(O)=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Fluconazole (mesylate) is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections. Fluconazole (mesylate) is the mesylate salt form of fluconazole, which is a triazole antifungal intended for oral treatment of superficial and systemic mycoses. In tests done in st and ard mycological media, the compound had minimal inhibitory concentrations against pathogenic C and ida species that were usually in excess of 100 mg/l. Fluconazole inhibited branching and hyphal development in C. albicans at concentrations as low as 10(-6) M (0.3 mg/l), but miconazole and ketoconazole were still active in these tests at concentrations 100 times lower than this . Oral fluconazole was not associated with a significantly increased risk of birth defects overall or of 14 of the 15 specific birth defects of previous concern. Fluconazole exposure may confer an increased risk of tetralogy of Fallot . Fluconazole is predicted to be ineffective against Cryptococcus gattii in the koala as a sole therapeutic agent administered at 10 mg/kg p.o. every 12 h . Clinical indications: Balanitis; C and ida infection; Cryptococcus infection; Cryptococcus neoformans meningitis; Dermatomycosis; Female genital tract infection; Fungal infection; Fungal respiratory tract infection; Fungal urinary tract infection; Prophylaxis; Tinea capitis; Tinea corporis; Tinea cruris; Tinea pedis . Toxicity: Symptoms of overdose include hallucinations and paranoid behavior. |
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