BMS-986165
Cat. No. :YN330156
CAS No. :1609392-27-9
86-020-82000279
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order@ubiochem.com| Product Name: | BMS-986165 |
| CAS NO.: | 1609392-27-9 |
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| Molecular Weight: | 425.46 |
| Molecular Formula: | C₂₀H₁₉D₃N₈O₃ |
| SMILES: | O=C(C1=NN=C(NC(C2CC2)=O)C=C1NC3=CC=CC(C4=NN(C)C=N4)=C3OC)NC([2H])([2H])[2H] |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | BMS-986165 is a highly selective, orally bioavailable allostericTYK2inhibitor for the treatment of autoimmune diseases, which selectively binds to TYK2 pseudokinase (JH2) domain (IC50=1.0nM) and blocks receptor-mediated Tyk2 activation by stabilizing the regulatory JH2 domain. BMS-986165 inhibitsIL-12/23 and type I IFNpathways. |
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