Upadacitinib
Cat. No. :YN340219
CAS No. :1310726-60-3
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order@ubiochem.com| Product Name: | Upadacitinib |
| CAS NO.: | 1310726-60-3 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 380.37 |
| Molecular Formula: | C₁₇H₁₉F₃N₆O |
| SMILES: | O=C(N1C[C@@H](CC)[C@@H](C2=CN=C3C=NC(NC=C4)=C4N32)C1)NCC(F)(F)F |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Upadacitinib (ABT-494) is a potent, orally active and selective Janus kinase 1 (JAK1) inhibitor (IC50=43nM). Upadacitinib (ABT-494) displays approximately 74 fold selective for JAK1 over JAK2 (200nM) in cellular assays dependent on specific, relevant cytokines. Upadacitinib (ABT-494) is used in development for the treatment of several autoimmune disorders. |
| IC50&Target: | |
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