SR-717
Cat. No. :YN330240
CAS No. :2375421-09-1
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5mg
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Product Name: | SR-717 |
CAS NO.: | 2375421-09-1 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 351.19 |
Molecular Formula: | C₁₅H₈F₂LiN₅O₃ |
SMILES: | O=C(O[Li])C1=CC(F)=C(F)C=C1NC(C2=NN=C(N3C=CN=C3)C=C2)=O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | SR-717 is a non-nucleotideSTINGagonist with EC50s of 2.1μM and 2.2μM in ISG-THP1 (WT) and ISG-THP1 cGAS KO (cGAS KO) cell lines, respectively. SR-717 is a stable cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) mimetic. Antitumor activity. |
IC50&Target: | |
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References: |
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