Danicopan
Cat. No. :YN330159
CAS No. :1903768-17-1
86-020-82000279
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order@ubiochem.com| Product Name: | Danicopan |
| CAS NO.: | 1903768-17-1 |
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| Molecular Weight: | 580.41 |
| Molecular Formula: | C₂₆H₂₃BrFN₇O₃ |
| SMILES: | O=C([C@H]1N(C(CN2N=C(C(C)=O)C3=C2C=CC(C4=CN=C(C)N=C4)=C3)=O)C[C@H](F)C1)NC5=NC(Br)=CC=C5 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Danicopan (ACH-4471), a selective and orally active small-moleculefactor Dinhibitor, shows high binding affinity to human Factor D withKdvalue of 0.54nM. Danicopan (ACH-4471) inhibits alternative pathway of complement (APC) activity, has potential to block the alternative pathway of complement in paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS). |
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