PAT-1251
Cat. No. :YN380032
CAS No. :2007885-39-2
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5mg
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Product Name: | PAT-1251 |
CAS NO.: | 2007885-39-2 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 399.34 |
Molecular Formula: | C₁₈H₁₇F₄N₃O₃ |
SMILES: | FC(F)(F)C1=NC(OC2=CC(C(N3C[C@@H](F)[C@H](O)C3)=O)=CC=C2)=CC(CN)=C1 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | PAT-1251 is a potent, selective and oral lysyl oxidase-like 2 (LOXL2) inhibitor, with IC50s of 0.71 and 1.17μM for hLOXL2 and hLOXL3, respectively, and also potently inhibits mouse, rat, and dog LOXL2 (IC50s, 0.10, 0.12, and 0.16μM, respectively); PAT-1251 is used in the research of fibrotic diseases. |
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References: |
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