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PAT-1251

Cat. No. :YN380032

  • CAS No. :2007885-39-2

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    • Products Infomation
    • Biological Activity
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    • Product Name:PAT-1251
      CAS NO.:2007885-39-2
      Chemical Name:
      Synonyms:
      Molecular Weight:399.34
      Molecular Formula:C₁₈H₁₇F₄N₃O₃
      SMILES:FC(F)(F)C1=NC(OC2=CC(C(N3C[C@@H](F)[C@H](O)C3)=O)=CC=C2)=CC(CN)=C1
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:PAT-1251 is a potent, selective and oral lysyl oxidase-like 2 (LOXL2) inhibitor, with IC50s of 0.71 and 1.17μM for hLOXL2 and hLOXL3, respectively, and also potently inhibits mouse, rat, and dog LOXL2 (IC50s, 0.10, 0.12, and 0.16μM, respectively); PAT-1251 is used in the research of fibrotic diseases.
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