Lanraplenib
Cat. No. :YN440121
CAS No. :1800046-95-0
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5mg
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Product Name: | Lanraplenib |
CAS NO.: | 1800046-95-0 |
Chemical Name: | |
Synonyms: | GS-SYK |
Molecular Weight: | 443.50 |
Molecular Formula: | C₂₃H₂₅N₉O |
SMILES: | NC1=CN=CC(C2=CN3C(C(NC4=CC=C(N5CCN(C6COC6)CC5)C=C4)=N2)=NC=C3)=N1 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Lanraplenib (GS-9876, GS-SYK) is a potent, highly selective and orally active inhibitor of Spleen Tyrosine Kinase (SYK) with IC50 of 9.5 nM. Lanraplenib inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans. |
IC50&Target: | |
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