MSA-2
Cat. No. :YN330270
CAS No. :129425-81-6
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order@ubiochem.com| Product Name: | MSA-2 |
| CAS NO.: | 129425-81-6 |
| Chemical Name: | |
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| Molecular Weight: | 294.32 |
| Molecular Formula: | C₁₄H₁₄O₅S |
| SMILES: | O=C(C1=CC(C(S1)=C2)=CC(OC)=C2OC)CCC(O)=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | MSA-2, a potent and orally available non-nucleotideSTINGagonist, hasEC50s of 8.3 and 24μM for human STING isoforms WT and HAQ, respectively. MSA-2 shows antitumor activity and stimulates interferon-β secretion in tumors, induces tumor regression with durable antitumor immunity, and synergizes with anti-PD-1 in syngeneic mouse tumor models. |
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