Quiflapon
Cat. No. :YN330009
CAS No. :136668-42-3
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order@ubiochem.com| Product Name: | Quiflapon |
| CAS NO.: | 136668-42-3 |
| Chemical Name: | |
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| Molecular Weight: | 587.17 |
| Molecular Formula: | C₃₄H₃₅ClN₂O₃S |
| SMILES: | O=C(O)C(C)(C)CC1=C(SC(C)(C)C)C2=C(C=CC(OCC3=NC4=CC=CC=C4C=C3)=C2)N1CC5=CC=C(Cl)C=C5 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Quiflapon (MK-591) is a selective and specific5-lipoxygenase-activating protein (FLAP)inhibitor with an IC50 of 1.6nM in a FLAP binding assay. Quiflapon is also a potent and orally activeLeukotriene biosynthesis (LT) inhibitor, showsIC50 values of 3.1 and 6.1nM in intact human and elicited rat PMNLs, respectively. Quiflapon induces cellapoptosis. |
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