W-54011
Cat. No. :YN330335
CAS No. :405098-33-1
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order@ubiochem.com| Product Name: | W-54011 |
| CAS NO.: | 405098-33-1 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 493.08 |
| Molecular Formula: | C₃₀H₃₇ClN₂O₂ |
| SMILES: | O=C(C1CCCC2=C1C=C(OC)C=C2)N(CC3=CC=C(N(C)C)C=C3)C4=CC=C(C(C)C)C=C4.[H]Cl |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | W-54011 is a potent and orally active non-peptideC5a receptorantagonist. W-54011 inhibits the binding of125I-labeledC5ato human neutrophils with aKivalue of 2.2nM. W-54011 also inhibitsC5a-induced intracellular Ca2+mobilization, chemotaxis, and generation ofROSin human neutrophils with IC50s of 3.1nM, 2.7nM, and 1.6nM, respectively. |
| IC50&Target: | |
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| References: |
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