HCH6-1
Cat. No. :YN480112
CAS No. :1435265-06-7
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order@ubiochem.com| Product Name: | HCH6-1 |
| CAS NO.: | 1435265-06-7 |
| Chemical Name: | |
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| Molecular Weight: | 469.53 |
| Molecular Formula: | C₂₈H₂₇N₃O₄ |
| SMILES: | O=C(N[C@H](C(N[C@@H](C(OC)=O)CC1=CC=CC=C1)=O)CC2=CNC3=C2C=CC=C3)C4=CC=CC=C4 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | HCH6-1 is a competitive antagonist of Formyl peptide receptor 1 (FPR1), an emerging therapeutic target for the discovery of drugs to treat neutrophilic inflammatory diseases. HCH6-1 is a selectiveFPR1inhibitor and has protective effects against acute lung injury (ALI). HCH6-1 inhibits superoxide anion generation, elastase release, and chemotaxis in human neutrophils activated by fMLF (an FPR1 agonist). |
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