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Jervine

Cat. No. :YN450143

  • CAS No. :469-59-0

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    • Product Name:Jervine
      CAS NO.:469-59-0
      Chemical Name:
      Synonyms:11-Ketocyclopamine
      Molecular Weight:425.60
      Molecular Formula:C₂₇H₃₉NO₃
      SMILES:O=C1[C@]2([H])[C@]3(C)C(C[C@@H](O)CC3)=CC[C@@]2([H])[C@]4([H])CC[C@]5(O[C@@]6([H])[C@@]([C@H]5C)([H])NC[C@@H](C)C6)C(C)=C41
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:Jervine is a Hedgehog signaling (IC50=500-700 nM) inhibitor that inhibits the sonic hedgehog (shh) pathway by interacting with smoothened.
      IC50&Target:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
      References:
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