Genkwanin
Cat. No. :YN251525
CAS No. :437-64-9
86-020-82000279
sales@ubiochem.com
order@ubiochem.com| Product Name: | Genkwanin |
| CAS NO.: | 437-64-9 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 284.26 |
| Molecular Formula: | C₁₆H₁₂O₅ |
| SMILES: | O=C1C=C(C2=CC=C(O)C=C2)OC3=CC(OC)=CC(O)=C13 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Genkwanin exerts its anti-inflammatory effect mainly through the regulation of the miR-101/MKP-1/MAPK pathway. Genkwanin is transported by both passive diffusion and multidrug resistance protein (MDR)-mediated efflux mechanisms. Genkwanin has antitumor activity partly via enhancing host immunity and decreasing the inflammatory cytokine levels, it may be an effective chemotherapeutic agent for the treatment of colorectal cancer. Genkwanin may have anti-skin ageing activity, it can up-regulate the transcriptional activation of human type vii collagen gene promoter, stimulating the formation of anchoring fibrils at the basement membrane zone in skin contributed to preventing skin ageing. Genkwanin induces a decrease of melanin synthesis by inhibiting tyrosinase activity, it could as skin whitening agent in cosmetic preparations. |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
TELL : +86-020-82000279
Add:Room 519, Block F, Guangzhou International Business Incubator, No.3 Lanyue Road, Science Town, Huangpu District, Guangzhou, China.
