FM-381
Cat. No. :YN340032
CAS No. :2226521-65-7
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order@ubiochem.com| Product Name: | FM-381 |
| CAS NO.: | 2226521-65-7 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 428.49 |
| Molecular Formula: | C₂₄H₂₄N₆O₂ |
| SMILES: | CN(C(/C(C#N)=C/C1=CC=C(C2=NC3=CN=C(NC=C4)C4=C3N2C5CCCCC5)O1)=O)C |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | FM-381 is a potent covalent reversible inhibitor ofJAK3targeting the unique Cys909. FM-381 has an IC50 of 127 pM for JAK3, with 410, 2700 and 3600-fold selectivity over JAK1, JAK2 and TYK2, respectively. |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
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| Solvent & Solubility: | |
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