ML604440
Cat. No. :YN370795
CAS No. :1140517-08-3
86-020-82000279
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order@ubiochem.com| Product Name: | ML604440 |
| CAS NO.: | 1140517-08-3 |
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| Molecular Weight: | 388.19 |
| Molecular Formula: | C₁₇H₂₄BF₃N₂O₄ |
| SMILES: | CC(C)C[C@@H](B(O)O)NC(C(NC(C1=CC=CC=C1C(F)(F)F)=O)(C)C)=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | ML604440 is a potent, specific and cell permeable proteasome β1i (LMP2) subunit inhibitor. ML604440 impairs MHC class I cell surface expression, IL-6 secretion and differentiation of naïve T helper cells to T helper 17 cells. ML604440 strongly ameliorates disease in experimental colitis and EAE. |
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