Oglemilast
Cat. No. :YN372263
CAS No. :778576-62-8
Product Name: | Oglemilast |
CAS NO.: | 778576-62-8 |
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Molecular Weight: | 516.30 |
Molecular Formula: | C₂₀H₁₃Cl₂F₂N₃O₅S |
SMILES: | O=C(C1=C2C(OC3=CC=C(NS(=O)(C)=O)C=C23)=C(OC(F)F)C=C1)NC4=C(Cl)C=NC=C4Cl |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Oglemilast (GRC 3886) is a potent and orally activephosphodiesterase-4 (PDE4)inhibitor with an IC50 of 0.5nM for PDE4D3. Oglemilast inhibits pulmonary cell infiltration, including eosinophilia and neutrophilia in vitro and in vivo. Oglemilast has the potential for inflammatory airway diseases . |
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