DRI-C21045
Cat. No. :YN270140
CAS No. :2101765-81-3
86-020-82000279
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order@ubiochem.com| Product Name: | DRI-C21045 |
| CAS NO.: | 2101765-81-3 |
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| Molecular Weight: | 580.61 |
| Molecular Formula: | C₃₂H₂₄N₂O₇S |
| SMILES: | O=S(C1=CC=CC2=CC=CC(NC(C3=CC=C(C4=CC=C(NC(C5=CC=C(C(OC)=O)C=C5)=O)C=C4)C=C3)=O)=C21)(O)=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | DRI-C21045 (compound 10) is a potent and selective inhibitor of theCD40-CD40Lcostimulatory protein-protein interaction (PPI) with an IC50 of 0.17 µM. DRI-C21045 shows concentration-dependent inhibition of the activation of NF-κB and B cell proliferation all induced by CD40L with IC50s of 17.1 µM and 4.5 µM, respectively. |
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