GSK717
Cat. No. :YN330268
CAS No. :1595278-21-9
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order@ubiochem.com| Product Name: | GSK717 |
| CAS NO.: | 1595278-21-9 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 452.55 |
| Molecular Formula: | C₂₈H₂₈N₄O₂ |
| SMILES: | O=C(NC1=CC=C2C(CCC2)=C1)CN3C4=CC=CC=C4N=C3CCN(C)C(C5=CC=CC=C5)=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | GSK717 is a potent, selectiveNOD2(nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signaling, with an IC50 of 400nM for MDP-stimulated IL-8 secretion in HEK293/hNOD2 cells. |
| IC50&Target: | |
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| In Vivo: | |
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| Solvent & Solubility: | |
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