PK68
Cat. No. :YN270199
CAS No. :2173556-69-7
86-020-82000279
sales@ubiochem.com
order@ubiochem.com| Product Name: | PK68 |
| CAS NO.: | 2173556-69-7 |
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| Molecular Weight: | 424.52 |
| Molecular Formula: | C₂₂H₂₄N₄O₃S |
| SMILES: | O=C(OC1CCCCC1)NC2=CC(C3=CC=C4N=C(NC(C)=O)SC4=C3)=CN=C2C |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | PK68 is a potent and selective type II inhibitor ofreceptor-interacting kinase 1 (RIPK1)with an IC50 of ~90 nM, displays inhibition of RIPK1-dependent necroptosis. PK68 powerfully ameliorates TNF-induced systemic inflammatory response syndrome, and with great potential for use in the treatment of inflammatory disorders and cancer metastasis. |
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