CCR2 antagonist 4
Cat. No. :YN320357
CAS No. :226226-39-7
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Product Name: | CCR2 antagonist 4 |
CAS NO.: | 226226-39-7 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 439.86 |
Molecular Formula: | C₂₁H₂₁ClF₃N₃O₂ |
SMILES: | O=C(NCC(N[C@H]1CN(CC2=CC=C(Cl)C=C2)CC1)=O)C3=CC=CC(C(F)(F)F)=C3 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | CCR2 antagonist 4 (Teijin compound 1) is a potent and specificCCR2antagonist, with IC50s of 180nM for CCR2b. CCR2 antagonist 4 potently inhibits MCP-1-induced chemotaxis with an IC50 of 24nM. |
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