Hypaconitine
Cat. No. :YN270454
CAS No. :6900-87-4
Product Name: | Hypaconitine |
CAS NO.: | 6900-87-4 |
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Molecular Weight: | 615.71 |
Molecular Formula: | C₃₃H₄₅NO₁₀ |
SMILES: | CO[C@@H](CC1)C23[C@@](C[C@@]4(O)[C@@H]5OC(C6=CC=CC=C6)=O)([H])[C@@]5([H])[C@](OC(C)=O)([C@@H](O)[C@@H]4OC)C7C2N(C)C[C@@]1(COC)[C@@]3([H])[C@H]7OC |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Hypaconitine, an active and highly toxic constituent derived from Aconitum species, is widely used to treat rheumatism. In vitro: The present study investigated the metabolism of hypaconitine in vitro using male human liver microsomes. The primary contributors toward HA metabolism were CYP3A4 and 3A5, with secondary contributions by CYP2C19, 2D6 and CYP2E1 . In vivo: |
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