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SPL-707

Cat. No. :YN380044

  • CAS No. :2195361-33-0

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    • Product Name:SPL-707
      CAS NO.:2195361-33-0
      Chemical Name:
      Synonyms:
      Molecular Weight:505.54
      Molecular Formula:C₂₇H₂₈FN₅O₄
      SMILES:CC1=C(NC(C[C@@H](C2CC2)C(N[C@@H]3C(N(CC4(CC4)C5)N5C(C6=C3C=CC=C6)=O)=O)=O)=O)C=C(F)C=N1
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:SPL-707 is an orally active, selectivesignal peptide peptidase-like 2a (SPPL2a)inhibitor with an IC50 of 77nM for hSPPL2a. SPL-707 inhibitsγ-secretase(IC50=6.1μM) and SPP(IC50=3.7μM). SPL-707 has the potential for autoimmune diseases research by targeting B cells and dendritic cells.
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