SHR0302
Cat. No. :YN340080
CAS No. :1445987-21-2
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price
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10mg
$ 1,300.00
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order@ubiochem.com| Product Name: | SHR0302 |
| CAS NO.: | 1445987-21-2 |
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| Molecular Weight: | 414.48 |
| Molecular Formula: | C₁₈H₂₂N₈O₂S |
| SMILES: | O=C(N1C[C@@]2([H])[C@@](C[C@H](N(C)C3=C4C(NC=C4)=NC=N3)C2)([H])C1)NC5=NC(OC)=NS5 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | SHR0302 is a potent and orally active all members of theJAK familyinhibitor, particularlyJAK1. The selectivity of SHR0302 forJAK1is >10-fold forJAK2, 77-fold forJAK3, 420-fold forTyk2. SHR0302 inhibitsJAK1-STAT3phosphorylation and induces theapoptosisof hepatic stellate cells. SHR0302 has anti-proliferative and anti-inflammatory effects. |
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