TC-S 7009
Cat. No. :YN372484
CAS No. :1422955-31-4
86-020-82000279
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order@ubiochem.com| Product Name: | TC-S 7009 |
| CAS NO.: | 1422955-31-4 |
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| Molecular Weight: | 308.65 |
| Molecular Formula: | C₁₂H₆ClFN₄O₃ |
| SMILES: | ClC1=CC(NC2=C([N+]([O-])=O)C3=NON=C3C=C2)=CC(F)=C1 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | TC-S 7009 is a potent and selectiveHIF-2αinhibitor with aKdof 81nM. TC-S 7009 is more selective forHIF-2αthan HIF-1α (Kd≫ 5μM). TC-S 7009 disruptsHIF-2αheterodimerization, decreases DNA-binding activity, and reducesHIF-2αtarget gene expression. |
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