C-021 dihydrochloride
Cat. No. :YN320260
CAS No. :1784252-84-1
Product Name: | C-021 dihydrochloride |
CAS NO.: | 1784252-84-1 |
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Molecular Weight: | 540.57 |
Molecular Formula: | C₂₇H₄₃Cl₂N₅O₂ |
SMILES: | COC1=CC2=NC(N3CCC(N4CCCCC4)CC3)=NC(NC5CCCCCC5)=C2C=C1OC.[H]Cl.[H]Cl |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | C-021 dihydrochloride is a potentCC chemokine receptor-4 (CCR4)antagonist. C-021 dihydrochloride potently inhibits functional chemotaxis in human and mouse with IC50s of 140nM and 39nM, respectively. C-021 effectively prevents human CCL22-derived [35S]GTPγS from binding to the receptor with an IC50 of 18nM. |
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