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C-021 dihydrochloride

Cat. No. :YN320260

  • CAS No. :1784252-84-1

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    • Product Name:C-021 dihydrochloride
      CAS NO.:1784252-84-1
      Chemical Name:
      Synonyms:
      Molecular Weight:540.57
      Molecular Formula:C₂₇H₄₃Cl₂N₅O₂
      SMILES:COC1=CC2=NC(N3CCC(N4CCCCC4)CC3)=NC(NC5CCCCCC5)=C2C=C1OC.[H]Cl.[H]Cl
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:C-021 dihydrochloride is a potentCC chemokine receptor-4 (CCR4)antagonist. C-021 dihydrochloride potently inhibits functional chemotaxis in human and mouse with IC50s of 140nM and 39nM, respectively. C-021 effectively prevents human CCL22-derived [35S]GTPγS from binding to the receptor with an IC50 of 18nM.
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